Illinois Route 66: Route 66 in 
Illinois generally follows Interstate-55 from  
Chicago to 
 St. Louis, 
 Missouri, criss-crossing the interstate, and meandering into the many small towns along the route. The State of 
Illinois has done a very good job of posting 
Route 66 with clearly marked signs, directing travelers when the road turns in the small towns and country roads. Many of the signs include both the new and 
old alignments.