Motel 66 Sign in Barstow, California. Photo by Carol Highsmith, 2012.

Indian troubles with the Paiute, Mojave and Chemehuevi tribes followed and from 1860 Camp Cady, a U.S. Army post 20 miles east of Barstow, was occupied sporadically until 1864, then permanently, by soldiers occupying other posts or patrolling in the region until 1871.