The Pottawatomi Baptist Mission Building is a historic mission off W 6th Street, one-half mile west of Wanamaker Road in Topeka, Kansas. It was built in 1849 and added to the National Register of Historic Places in 1971. Today, it is part of the Kansas Museum of History. It was built to serve Pottawatomi Indians who had been forcibly removed from the Ohio region to a reservation on the Kansas River west of Topeka in 1838, along the Potawatomi Trail of Death.